Компания «Биолонг» совместно с РНЦ Восстановительной медицины и курортологии МЗСР РФ (Москва) и Военно-медицинской академией им. С.М. Кирова (Санкт-Петербург) разработала, испытала и производит новое средство комплексного воздействия на различные звенья патогенеза, обусловленные острой и хронической кислородной недостаточностью – средство для принятия ванн «Биолонг 1» и «Биолонг 3», являющееся эффективным средством профилактики и лечения последствий воздействия на организм радиационного облучения.
Применение средства для ванн «Биолонг®»
при радиоактивном загрязнения среды
Человеческий организм на 70 % состоит из воды, поэтому при воздействии радиации в первую очередь происходит ее радиолиз. В результате появляются «горячие» электроны и крайне опасные гидроксильные радикалы, способные повреждать любые важные структуры клеток. «Горячие» электроны связываются с присутствующим в тканях кислородом и превращаются в супероксидные ион-радикалы, негативные последствия появления которых таковы:
- структурные повреждения хромосом — наиболее важные генетические повреждения при радиации — когда нестабильные хромосомные аберрации приводят к гибели клеток, которые заменяются рыхлой соединительной тканью, а стабильные хромосомные аберрации создают дополнительные риски онкологических новообразований,
- нарушение процесса аэробного синтеза АТФ в результате разрушения митохондриального фермента аконитазы,
- связывание вырабатываемого клетками эндотелия оксида азота, что приводит к ограничению доставки клеткам кислорода и развитию тканевой гипоксии и ускоренному старению клетки или гибели клетки,
- образование в результате последующих модификаций более стабильных и опасных для клеток вторичных радикалов, которые ведут к:
- повреждению ДНК (развитие онкологии или других соматических заболеваний),
- повреждению мембранных структур (клеточная дистрофия или гибель),
- нарушению Redox-гомеостаза клеток, что сопровождается нарушением экспрессии ряда генов и вызывает дезорганизацию работы клеточных ферментов (например, экспрессия сиртуиновых генов, являющихся ключевыми регуляторами многих важнейших клеточных процессов, зависит именно от Redox-состояния внутриклеточной среды).
Средство для принятия ванн «Биолонг®» — средство выбора для профилактики патологий, как последствий радиационного облучения
Композиция для ванн «Биолонг®» разработана в качестве средства комплексного воздействия на различные звенья патогенеза, обусловленные острой и хронической кислородной недостаточностью. Базовым действующим веществом является антиоксидант-антигипоксант «Митофен®» — вещество нового поколения.
- Митофен органично замещает функции недееспособных участков дыхательной цепи митохондрий
- Митофен, является ловушкой для «горячих» электронов и существенно снижает вероятность появления первичных радикалов — активных форм кислорода (АФК) и продуктов перекисного окисления липидов (ПОЛ),
- Митофен обладает супероксидазной активностью и разрушает супероксидные ион-радикалы,
- Митофен снижает число хромосомных аберраций, в том числе, в лейкоцитах крови,
- Митофен обладает выраженной антиоксидантной активностью, препятствует снижению мембранного потенциала и связывает образующиеся вторичные радикалы,
- Митофен способствует нормальной работе репарационной системы, требующей больших энергетических затрат в лимитированное время, что позволяет эффективно восстанавливать поврежденные структуры,
- Митофен способствуют повышению линейной скорости кровотока в тканях и устраняют венозную дисфункцию, тем самым оптимизируя доставку клеткам необходимых продуктов и вывод от них отработанных «шлаков».
Эффективность профилактического и лечебного воздействия Митофена на организм облученных подтверждена экспериментально.
В профилактических целях в условиях повышенного радиационного фона показано ежедневное применение Биолонга в виде бальнеопроцедур (50 мл средства для ванн «Биолонг 1» растворяются в стандартной 200 л ванне, процедуры принимать в течение 20-25 минут при температуре воды не выше 37-38°C). Общий курс не менее 10-12 процедур.
В лечебных целях в условиях повышенного радиационного фона, а также после критического облучения показано незамедлительное и впоследствии двукратное ежедневное применение Биолонга в виде бальнеопроцедур (50 мл средства для ванн «Биолонг 3» растворяются в стандартной 200 л ванне, процедуры принимать в течение 20-25 минут при температуре воды не выше 37-38°C). Общий курс не менее 20 процедур.
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